Tumor Necrosis Factor α Regulates Collagenolytic Activity in Preovulatory Ovine Follicles: Relationship to Cytokine Secretion by the Oocyte-Cumulus Cell Complex1
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چکیده
منابع مشابه
Programmed cell death in preovulatory ovine follicles.
Apoptosis is a mode of physiological cell death that occurs during tissue regression and remodeling; it is characterized by macromolecular protein synthesis, oligonucleosomal fragmentation, nuclear condensation, cytoplasmic shrinkage, and dissociation of cell-to-cell junctional complexes. Direct in situ fluorescence detection of digoxigenin end-labeled genomic DNA was used as a marker of nuclea...
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The role of gossypol in the cumulus expansion of oocyte-cumulus complexes (OCC) isolated from large antral porcine follicles was investigated. Marked suppression of cumulus expansion stimulated with follicle-stimulating hormone (FSH) and epidermal growth factor (EGF) was observed in the presence of different concentrations of gossypol. Comparable inhibitory effects were obtained in the presence...
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Adipogenesis is tightly regulated by altering gene expression, and TNF-α is a multifunctional cytokine that plays an important role in regulating lipogenesis. MicroRNAs are strong post-transcriptional regulators of cell differentiation. In our previous work, we found high expression of miR-181a in a fat-rich pig breed. Using bioinformatic analysis, miR-181a was identified as a potential regulat...
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Objective(s): To observe and determine the effect and mechanism of psoralen on tumor necrosis factor-α (TNF-α)-induced muscle atrophy.Materials and Methods: Three sets of C2C12 cells, including blank control, TNF-α (10 or 20 ng/ml) treatment and a TNF-α (10 or 20 ng/ml) plus psoralen (80 μM) administration were investigated. Cell viabili...
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ژورنال
عنوان ژورنال: Biology of Reproduction
سال: 1999
ISSN: 0006-3363,1529-7268
DOI: 10.1095/biolreprod61.6.1581